Leptin Metabolically Licenses T Cells for Activation To Link Nutrition and Immunity
نویسندگان
چکیده
منابع مشابه
Leptin metabolically licenses T cells for activation to link nutrition and immunity.
Immune responses are highly energy-dependent processes. Activated T cells increase glucose uptake and aerobic glycolysis to survive and function. Malnutrition and starvation limit nutrients and are associated with immune deficiency and increased susceptibility to infection. Although it is clear that immunity is suppressed in times of nutrient stress, mechanisms that link systemic nutrition to T...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2013
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.1301158